摘要
目的:评价急性心肌梗塞(AMI)与非急性心肌梗塞伴阵发性心房颤动(PAF)静脉应用胺碘酮的疗效。方法:选择23例AMI及20例非AMI伴PAF患者,应用胺碘酮5mg/kg的负荷量后,给予10~20mg/kg.d维持,24h量不超过2200mg。结果:房颤转复率:AMI组100%,非AMI组70%(14/20),差异有显著性(P<0.05);转复时间:AMI组(2063±140)min,非AMI组(215±138)min,两组差异无统计学意义(P<0.05)。结论:胺碘酮治疗AMI并发阵发性房颤患者转复率高,安全、可靠,可作为首选用药。
Objective:To evaluate effectiveness of intravenous amiodarone in treating patients with or without acute myocardial infarction(AMI)complicated with paroxysmal atrial fibrillation(PAF).Methods:The 23 patients with AMI and 20 patients without AMI complicated PAF were given load dosage of amiodarone 5 mg/kg,then maintenance dosage of 10~20/kg·d.Maximum dosage was less than 2 200 mg during 24 h.Results:The cardioversion rate of PAF in AMI group was 100%,in control group was 70%,there was statistical difference between two groups(P〈0.05).For cardioversion time,it of AMI group was(2063±138)min,there was no statistical difference between two groups(P〉0.05).Conclusion:Treating AMI or non-AMI patients complicated with paroxysmal fibrillation by using amiodarone has much higher cardioversion rate and is safe.
出处
《心血管康复医学杂志》
CAS
2007年第4期389-391,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
胺碘酮
心肌梗塞
心房颤动
Amiodarone
Myocardial infarction
Atrial fibrillation