期刊文献+

氯沙坦联用美托洛尔治疗慢性充血性心力衰竭的疗效

下载PDF
导出
摘要 目的探讨氯沙坦联用美托洛尔治疗慢性充血性心力衰竭(CHF)的临床疗效。方法将72例CHF患者随机分成2组,观察组(36例)给予氯沙坦25~100mg1次/d,美托洛尔6.25mg2次/d,如无不良反应,每2周剂量倍增;对照组给予氯沙坦25~100mg1次/d。两组疗程均6个月。结果两组治疗前后心功能、左室舒张末期内径(LVEDd)、左室收缩末期内径(LVESd)、左室射血分数比较,均明显改善(P<0.05),治疗后观察组优于对照组(P<0.05)。结论采用氯沙坦联用美托洛尔治疗CHF患者疗效优于单用氯沙坦,且耐受性好。
出处 《现代实用医学》 2007年第8期609-610,622,共3页 Modern Practical Medicine
  • 相关文献

参考文献12

二级参考文献40

  • 1[1]Packer M,Conh JN,Abraham WT,et al.Cosenus recommendation for the managemeat of chronic heart failure.Am J Cardiol,1999,83:(2):1A-38A.
  • 2[2]The Captoril,Digoxin Multicenter Research Group.Comparative offects of therapy with captopril and digoxin in patients with mild to moderate heart failure.JAMA,1998,259:359-544.
  • 3[3]The WOL VD Investigators.Effect of enalapril on survival in patents with reduced lef ventricular ejection fraction,and congestive heart failure.N Engl J Med,1991,325:293-302.
  • 4[4]Cohn JN,Johnson G,Ziesche S,et al.A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestine heart failure.N Gngl J Med,1991,352:303-310.
  • 5[5]The CONSENSUS tyial study Goup.Effects of enalapril on mortality in severe congestive heart faliure:Results of the cooperative North scandinavial Enalapril Survial Study(CONSENSUS).Nengl J Med,1987,316:1 429-1 435.
  • 6[6]Waagstein F,Bristow MR,Swedberg K,et al.Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy.Lancet,1993,342:1 441-1 446.
  • 7[7]Tsuyuki RT,Yusuf S,Rouleau JL,et al.Combination neurohormonal blockade with ACE inhibitors,angiotensin Ⅱ antagonists and beta-blockers in patients with congestive heart failure:Design of the Randomized Evaluation of Strategies for Left Ventricular Dysfunciton(RESOLVD)Pilot study.Can J Cardiol,1997,13(12):1 166-1 174.
  • 8[8]The Intemation Steering Commtittee.Rrational,desing,and organization of the metoprolo CR/XL randomized intervention trial in heart failure(MERIT-HF).Am J Cardiol,1997,80(Suppl 9B):54J-58J.
  • 9[9]BCIBIS Ⅱ Investigation and Committees.The Cardiac Insufficiency Bisoprolol study(CIBIS Ⅱ):a randomized trial.Lancet,1999,353:9-13.
  • 10[10]Packer M,Colucci WS,Sackner-Bernstein JD,et al.Double-blind,Placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure.The PRECISE trial.Prospective Randomized Evaluation of Carvedilol on Symptoms and Exercise.Circulation,1996,94:2 793-2 799.

共引文献2502

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部