术洁碘消毒液杀菌效果与稳定性观察

Germicidal Effects and Stability of Shu-Jin Iodine Disinfection Solution

目的观察术洁碘消毒液对微生物的杀灭效果及其稳定性。方法采用悬液定量杀菌试验观察其杀灭微生物效果,加速试验及自然挥发法观察其稳定性。结果术洁碘消毒液150 mg/L有效碘,作用1 min,300 mg/L有效碘,作用0.5 min,大肠埃希菌和金黄色葡萄球菌的杀灭对数值>5.00,白色假丝酵母菌的杀灭对数值>4.00;37℃放置90 d,或暴露于空气连续6 d,每天6 h,有效碘含量及样品质量数轻度变化;涂擦皮肤1遍,作用1 min,自然菌的杀灭对数值>1.00。结论术洁碘消毒液杀灭微生物效果好,且性质稳定。

OBJECTIVE To evaluate the germicidal effects and stability of the Shu-Jin iodine disinfection solution. METHODS Suspension quantitative germicidal test was used to observe its germicidal effects, while stability and volatile test was adopted to monitor its stability. RESULTS The germicidal logarithmic value was 〉 5. 0 to Staphylococcus aureus and Escherichia coli, 〉4. 0 to Candida albicans in the 150 mg/L of available iodine concentration for 1 min,or 300 mg/L of available iodine concentration for 0.5 min,respectively. After being stored at 37 ℃ for 90 days or exposured 6 h per-day in consecutive 6 days, the available iodine content of the stock solution and quality of the sample slightly changed. The germicidal logarithmic value was more than 1.00 to the forearm skin natural bacteria when smeared 1 time for 1 min. CONCLUSIONS The germicidal effects of Shu-Jin iodine disinfection solution is good and stable.