宫颈癌靶向治疗进展
摘要
随着近年宫颈癌的发病率增高及发病年龄渐趋年轻化,治疗后对生活质量的要求明显提高,随着对新的肿瘤特异位点的不断认识及由于免疫学和分子生物学的发展,以肿瘤形成过程中的受体、基因和信号转导为靶向的新的靶向治疗药物不断涌现。宫颈癌治疗模式需要进一步研究探索和改变。
出处
《国外医学(妇产科学分册)》
2007年第4期237-240,共4页
Foreign Medical Sciences(Obstet Gynecol Fascicle)
参考文献20
-
1Jiang M, Milner J. Selective silencing of viral gene E6 and E7 expression in HPV-positive human cervical carcinoma cells using small interfering RNAs [ J ]. Methods Mol Biol, 2005,29(2): 401-420.
-
2Somasundaram KDS. Therapeutic potential of an adenovirus expressing p73beta, a p53 homologue, against human papilloma virus positive cervical cancer in vitro and in vivo[J]. Cancer Biol Ther, 2006, 5 (2): 210-217.
-
3Perez-Cardenas E, Contreras-Paredes A, Cantu D, et al. The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study[J]. Virol J, 2007, 26(4): 18-19.
-
4Park EK, Jin HS, Lee JM, et al. Immunization with adenoviral vectors carrying recombinant IL-12 and E7 enhanced the antitumor immunity to human papillomavirus 16-associated tumor[J]. Gynecol Oncol, 2005, 97(2): 559-567.
-
5Green KL, Southgate TD, Mulryan K, et al. Diffusible VP22-E2 protein kills bystander cells and offers a route for cervical cancer gene therapy[J]. Hum Gene Ther, 2006, 17(2): 147-157.
-
6Straughn JM Jr, Oliver PG, Zhou T, et al. Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer modei[ J ]. Gynecol Oncol, 2006, 101(1): 46-54.
-
7Sethi N, Palefsky J. Treatment of human papillomavirus (HPV) type 16 infected cells using herplex simplex virus typelthymudine kinase mediated gene therapy transcriptionally regulated by the HPV E2 protein [J]. Hum Gene Ther, 2003,14(1): 45-57.
-
8Hsieh FC, Lieblein JC, Brown J, et al. Stat3 activation in human endometrial and cervical cancers[J]. Br J Cancer, 2007, 26, 96(4): 591-599.
-
9Rincon-Arano H, Rosales R, Mora N, et al. R-Ras promotes tumor growth of cervical epithelial cells[J]. Cancer, 2003, 97(3): 575- 585.
-
10Vaidya AP, Parries AD, Seiden MV. Rationale and clinical experience with epidermal growth factor receptor inhibitors in gynecologic malignancies [ J ]. Curr Treat Options Oncol, 2005, 6(2): 103-114.
-
1基因检测结合靶向治疗让脑瘤不再复发[J].医药前沿,2016,0(14):3-4.
-
2陈文明.多发性骨髓瘤的靶向治疗[J].白血病.淋巴瘤,2009,18(9):523-528. 被引量:2
-
3胃间质瘤靶向治疗效果好不好[J].大众医学,2016,0(2):66-66.
-
4张述升,张飚,王金环.转化生长因子-β受体Ⅲ负性调控肿瘤发生的研究[J].国际肿瘤学杂志,2012,39(6):411-414. 被引量:1
-
5曹丽,苏园园,韩燕华.女性压力性尿失禁研究进展[J].新医学,2008,39(7):481-483. 被引量:19
-
6宣毅,宣伟军.脑损伤模型中基于形态学多重免疫荧光技术的神经细胞研究方法[J].中华神经医学杂志,2015,14(11):1118-1121. 被引量:1
-
7李子明,陆舜.非小细胞肺癌靶向治疗新进展[J].肿瘤研究与临床,2010,22(1):7-10.
-
8杨艳华,谢青.慢性丙型肝炎特异性靶向治疗药物的研究进展[J].肝脏,2008,13(1):81-82.
-
9服靶向药物 掌握好时间[J].中国社区医师,2009(12):27-27.
-
10服靶向药物 掌握好时间[J].中国社区医师(医学专业),2009(9):104-104.