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雌激素受体在卵巢癌发生发展中作用的研究进展 被引量:6

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摘要 卵巢癌是常见的妇科恶性肿瘤之一。因缺乏有效的诊断方法,确诊时多为晚期,死亡率居妇科恶性肿瘤首位。大量流行病学调查已显示雌激素与卵巢癌的发生有关,而且在卵巢上皮肿瘤的病程进展中起重要作用,雌激素主要通过雌激素受体(ER)启动一系列的信号传导途径。因此,ER是雌激素与卵巢癌间的重要桥梁,对ER的研究有助于指导卵巢癌的临床治疗,就卵巢癌中ER自身状态及细胞因子对其影响综述。
出处 《国外医学(妇产科学分册)》 2007年第4期254-257,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
基金 国家自然科学基金(编号:30572096)
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