摘要
目的:研究生姜油(Ginger oils)对肝脏的保护作用。方法:通过复制四氯化碳和醋氨酚急性肝损伤小鼠模型,观察生姜油的保肝作用。结果:生姜油可显著降低四氯化碳和醋氨酚致小鼠急性肝损伤的ALT和AST水平(P<0.05,P<0.01);并能显著降低小鼠血清和大鼠肝组织的MDA含量(P<0.05,P<0.01),升高小鼠血清和鼠肝组织的SOD活性(P<0.05)。结论:生姜油对四氯化碳和醋氨酚致急性肝损伤具有明显的保护作用。
AIM ： To investigate the protective effect of ginger oil on liver. METHODS ： Mouse model of acute hepatic injury induced by carbon tetrachloride and acetaminophen were used to observe the protective effect of ginger oil on liver. RESULTS ： Ginger oil could obviously decrease ALT and AST levels of mouse model of acute hepatic injury induced by carbon tetrachloride and acetaminophen, significantly decrease MDA level of rat liver tissue and mouse serum （P 〈0.05 ,P 〈0.01 ） ,increase.activity of SOD of mouse liver tissue and serum. CONCLUSION： Ginger oil has obviously protective effect on acute hepatic injury induced by carbon tetrachloride and acetaminophen.
出处
《中成药》
CAS
CSCD
北大核心
2007年第8期1123-1126,共4页
Chinese Traditional Patent Medicine
关键词
生姜油
保肝作用
抗氧化
小鼠
ginger oils
protective effect on liver
anti-oxidation
mouse
