纳络酮治疗急性乙醇中毒疗效观察

Therapeutic study of nalooxone on acute alcoholism

目的：观察纳络酮治疗急性乙醇中毒的疗效。方法：将2006年我院急诊科急性乙醇中毒病例，按入院先后次序随机分为治疗组和对照组，对照组使用10％葡萄糖1000mL＋维生素C2．0g、维生素B60．1g静脉滴注，呋塞米20mg静脉注射（血压低者不用）；治疗组用盐酸纳洛酮0．4～0．8mg＋10％葡萄糖40mL静脉注射治疗，根据病情酌情维持治疗。比较两组的治疗效果。结果：治疗组疗效明显优于对照组（P〈0．01）。结论：纳洛酮治疗急性乙醇中毒疗效好，值得临床推广应用。

Objective： To evaluate the therapeutic effect of Nalooxone on acute alcoholism. Methods： Patients with acute alcoholism in 2006 were devided into two groups randomly. Group A： treated by 10% glucose with vitamin C 2. 0g and vitamin B6 0. lg, Furosemide 20mg iv （But not for patients with low blood pressure）. Group B： treated by Nalooxone 0.4-0. 8mg iv drip and extra dosage continued according to patients condition. The results of two groups were compared. Results. Group treated with Nalooxone showed better effect （P〈0.01）. Conclusion： Nalooxone has positive effect on acute alcoholism and it is recommendable for acute alcoholism.