针刺“四缝”穴对实验性脾虚大鼠血清锌及胃排空率的影响

Effects of acupuncture at "Sifeng" (EX-UE 10) on serum zinc and gastric emptying rate in the rat of experimental spleen deficiency

目的:探讨针刺"四缝"穴对小儿厌食症的作用机制。方法:对健康Wistar大鼠随机分组,设正常组、模型组和针刺组。采用肌注利血平注射液造模,针刺组每天点刺"四缝"穴1次,连续2w。然后观察各组胃排空速率、血液中红细胞Zn、血清Zn含量。结果:①与模型组比较,针刺组对大鼠有加速胃排空作用,差异有非常显著性意义(P<0.01);②针刺组可提高大鼠血清Zn含量,与模型组比较差异有显著性意义(P<0.05)。结论:针刺"四缝"穴对大鼠的脾虚模型有明显治疗作用。其作用机制为加快胃排空速率,提高血清及红细胞Zn的含量。

Objective To probe the mechanism of acupuncture at Sifeng （EX-UE 10） for treatment of infant anorexia. Methods Healthy rats were randomly divided into a control group, a model group and an acupuncture group. The model rats were made by intramuscular injection of Reserpine. The acupuncture group were treated with pricking at Sifeng （EX-UE 10） once daily for 2 weeks. After that, the gastric emptying rate and contents of Zn in the red cell and serum were observed in all the groups. Results Compared with the model group, the gastric emptying rate was accelarated, and the serum Zn content was increased in the acupuncture group （P〈0. 01, P〈0. 05）. Conclusion Acupuncture at Sifeng （EX-UE 10） has significant therapeutic effect on the rat with spleen deficiency, accelerating the gastric emptying rate and increasing the serum Zn content.