兔椎体骨折愈合过程的X线、MRI表现与病理学变化对照研究

Correlative study of the X-ray, MRI manifestations of the process of vertebral fracture healing in rabbit with pathologic findings

目的:探讨X线、MRI对兔椎体骨折及其愈合过程的评判价值。方法:选年龄、体重均相近的健康成年雌性青紫兰兔21只,手术制成椎体骨折后,分别在骨折后的24小时、72小时、1周、2周、4周、6周、8周观察其愈合的X线、MRI表现,并与其病理学改变对照分析。结果:随着骨折的修复,在平片上,骨折椎体内的低密度骨折线逐渐被带状致密影所代替,骨折椎体密度增高最终恢复为等密度;在MRI上,逐渐由长T1、长T2信号恢复为等T1等T2信号。结论:平片可通过对兔骨折椎体密度的分析评判其愈合的程度;MRI的信号改变在一定程度上能反映出兔椎体骨折愈合过程中的病理学改变。

Objective： To evaluate the value of MRI and CR in the diagnosis of healing process of vertebral fracture. Methods： Twenty-one healthy adult female rabbits of the same age and weight were selected, firstly, animal models of vertebral fracture were made by operation, then they were examined with CR and MRI at 24 hours, 72 hours, 1 week, 2 weeks, 4 weeks, 6 weeks, 8 weeks respectively. MRI/CR manifestations and pathological appearances were analyzed. Results： With the repairing of the fractured vertebra, on CR, the low density band was substituted by high density band, the density of the fractured vertebra increased, and in the end, resumed equal to the adjacent vertebra. On MRI, the low signal intensity on T1WI and high signal intensity on T2WI resumed isointense on T1WI and T2WI. Conclusion： CR has some value to the diagnosis of vertebral fracture and the healing process of the rabbit by analyzing density of the callus. The signal intensity of MRI could reflect the pathology of vertebral fracture of rabbit to some extent.