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神经再生内环境研究的新进展 被引量：2

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摘要 外周神经再生是外周神经外科领域内的一个老大难问题，长期以来还没有解决，主要有三个难题：第一，外周神经比较娇嫩，容易受伤，轻微外力都容易被撕裂，断裂端又会退缩，形成缺损。即使轴突还完整，但每因神经出血、水肿、最后会导致瘢痕化，难以恢复功能。加上交通日益发达，经常发生超速超载，事故也频频发生，臂丛、坐骨神经、桡神经等损伤，有增无减；
作者 朱家恺 曾园山
机构地区 中山大学附属第一医院显微外科 中山大学中山医学院组织胚胎学教研室
出处 《中华显微外科杂志》 CSCD 北大核心 2007年第4期244-246,共3页 Chinese Journal of Microsurgery
关键词 外周神经再生 内环境 外科领域 恢复功能 坐骨神经 瘢痕化 桡神经
分类号 R651 [医药卫生—外科学]
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参考文献8

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同被引文献56

  • 1顾玉东.提高周围神经损伤的诊治水平[J].中华创伤骨科杂志,2003,5(1):1-4. 被引量：60
  • 2Pettersson J, Mcgrath A, Kalbennatten DF, et al. Muscle recovery after repair of short and long peripheral nerve gaps using fibrin conduits. Neurosci Lett,2011,500 :41-46.
  • 3Udina E, Cobianchi S, Allodi I, et al. Effects of activity- dependent strategies on regeneration and plasticity after peripheral nerve injuries. Ann Anat ,201 l, 193:347-353.
  • 4Tansey KE, Seifert JL, Botterman B, et al. Peripheral nerve repair through multi-luminal biosynthetic implants. Ann Biomed Eng, 2011,39 : 1815-1828.
  • 5Karabekmez FE, Duymaz A, Moran SL. Early chnical outcomes with the use of decellularized nerve allograft for repair of sensory defects within the hand. Hand ( NY ) , 2009, 4 : 245 -249.
  • 6Brooks DN ,Weber RV ,Clmo JD ,et al. Processed nerve allografts for peripheral nerve reconstruction: a multieenter study of utilization and outcomes in sensory, mixed, and motor nerve reconstructions. Microsurgery ,2012,32 : 1-14.
  • 7Cho MS, Rinker BD, Weber RV, et al. Functional outcome following nerve repair in the upper extremity using processed nerve allograft. J Hand Surg Am ,2012,37:2340-2349.
  • 8Meek MF. A randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans. Plast Reconstr Surg,2001,108 : 1087-1088.
  • 9Meek MF, Nicolai JP, Robinson PH. Secondary digital nerve repair in the foot with resorbable p(DLLA-epsilon-CL) nerve conduits. J Reconstr Microsurg, 2006,22 : 149-151.
  • 10Lohmeyer JA, Siemers F, Machens HG, et al. The clinical use of artificial nerve conduits for digital nerve repair: a prospective cohort study and literature review. J Reconstr Microsurg, 2009,25 : 55-61.

引证文献2

二级引证文献25

中华显微外科杂志
2007年 第4期

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