期刊文献+

全身麻醉对胆囊切除术患者白细胞介素-6的影响

下载PDF
导出
摘要 目的观察全身麻醉对病人围术期白细胞介素-6(IL-6)的影响。方法选择择期胆囊切除手术60例,ASA评分I^II级,随机分为2组:全凭静脉麻醉组(Ⅰ组,n=30)和静吸复合麻醉组(Ⅱ组,n=30)。在全麻诱导前,诱导后麻醉前,切皮后90 min、4h采血3ml,采用ELISA法测定IL-6。结果在切皮后、4h、12 h两组IL-6浓度较麻醉前均有显著增加,两组组间比较有统计学差异(<0.05)。结论控制术中炎症反应程度全凭静脉麻醉组优于静吸复合麻醉组,可以使患者术中、术后更平稳。
出处 《医学新知》 CAS 2007年第4期232-233,共2页 New Medicine
  • 相关文献

参考文献5

  • 1范隆,王国林.咪达唑仑和丙泊酚对炎性反应的影响[J].国外医学(麻醉学与复苏分册),2005,26(1):48-51. 被引量:9
  • 2Kotani N, Hashimoto H, Seeeler D I, et al. Cardiopulmonary by-pass produces greater pulmonary than systemic proinflammatory cytokines.Anesth Analg, 2000,90: 1039
  • 3Marina M, Apostolos G, Vagenakis, et,al. Dissociation of the Early Decline in Serum T3 Concentration and Serum IL-6 Rise and TNFα in Nonthyroidal Illness Syndrome Induced by Abdominal Surgery. The Journal of Clinical Endocrinology & Metabolism ,2002, 86(9): 4198
  • 4Kotani N, Hashimoto H, Sessler D L, et al, Supplemental intra- operative oxygen augments antimicrobial and proinflammatory responses of alveolar macrophages. Anesthesiology, 2000, 93 (1): 15.
  • 5吴云,王焱林,刘茂春,饶艳.瑞芬太尼和芬太尼对LPS诱导的细胞因子的影响[J].武汉大学学报(医学版),2006,27(4):465-467. 被引量:9

二级参考文献33

  • 1韩传宝,钱燕宁,周钦海.术后镇痛对机体应激反应的调控[J].国外医学(麻醉学与复苏分册),2005,26(2):74-77. 被引量:76
  • 2Beilin B,Shavit Y,Hart J,et al.Effect of anesthesia based on large versus small doses of fentanyl on natural killer cell cytotoxicity in the perioperative period[J].Anesth Analg,1996,59:127-133.
  • 3Sacerdote P,Gaspani L,Rossoni G,et al.Effect of the opioid remifentanil on cellular immune response in the rat[J].International Immmmunopharmacology,2001,713-719.
  • 4Sheeran P,Hall GM.Cytokines in anaesthesia[J].Br J Anesth,1997,78:201-209.
  • 5Kawasaki T,Ogata M,Kawasaki C,et al.Ketamine suppresses proinflammatory cytokine production in human whole blood in vitro[J].Anesth Analg,1999,89:665-669.
  • 6Rosow CE.An overvien of remifentanil[J].Anesth Analg,1999,89:451-453.
  • 7Cortinez LI,Munoz HR,De la Fuente R,et al.Targetcontrolled infusion of remifentanil or fentanyl during extra-corporeal shock-wave lithotripsy[J].Eur J Anaesthesiol,2005,22:56-61.
  • 8Galley HF, Dubbels AM, Webster NR, et al. The effect of midazolam and propofol on interleukin-8 from human polymorphonuclear leukocytes. Anesth Analg, 1998,86(6): 1289-1293.
  • 9O'Donnell NG, Mcsharry CP, Wilkinson PC, et al. Comparison of the inhibitory effect of propofol, thiopentone and midazolam on neutrophil polarization in vitro in the presence or absence of human serum albumin. Br J of Anaesth, 1992,69(1 ) :70-74.
  • 10Hulse D, Kusel JR, O'Donell NG, et al. Effect of anesthetics on the mem brane mobility and locomotor responses of human neutrophils. FEMS lmmunol Med Microbiol, 1994,8(3):241-248.

共引文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部