外周动静脉同步换血治疗新生儿重症高胆红素血症的疗效研究

Curative effect of peripheral arteriovenous synchronous exchange transfusion on severe neonatal hyperbilirubinemia

目的研究新生儿外周动静脉同步换血疗法。方法100例新生儿重症高胆红素血症分二组。50例治疗组(换血组),50例对照组(光疗+药物),观察两组的治疗效果。结果治疗组疗效优于对照组。结论新生儿外周动静脉同步换血,操作简单、安全、无明显并发症,可迅速清除血中游离的间接胆红素、抗体、致敏红细胞,纠正贫血,阻止胆红素脑病的发生。临床疗效满意,值得推广。

Objective To study the effect of synchronous exchange transfusion in peripheral artery and vein in neonates. Methods 100 neonates with severe hyperbilirubinemia were divided into 2 groups. 50 cases were in treatment group （exchange transfusion） and other 50 in control group（phototherapy and medicine）. The therapeutic effects of 2 groups were observed. Results The effectiveness in treatment group was significantly superior to that in control group （P〈0. 05）. Conclusion Synchronous exchange transfusion in peripheral artery and vein in neonates is simple and safe with few complications. It can rapidly eliminate free indirect bilirubin, antibodies, sensitized erythrocytes from blood, and improve anemia and retard the occurrence of bilirubin encephalopathy. Considering its satisfying curative effect, it is worthy to he popularized.