乌拉地尔、多巴胺、呋塞米静脉滴注治疗心肾综合征

Urapidil,dopamine and furosemide for treatment of cardiorenal syndrome

目的了解乌拉地尔、多巴胺、呋塞米联合静滴治疗心肾综合征的疗效。方法25例心肾综合征患者经利尿剂、血管扩张剂、洋地黄类药物等常规抗心力衰竭治疗无效后,在此治疗基础上加用乌拉地尔、多巴胺、呋塞米联合静滴,以7天为一疗程进行疗效观察。结果加用乌拉地尔、多巴胺、呋塞米治疗后心功能明显改善,总有效率92%;超声心动图检测左心室功能指标、血生化检测血尿素氮(BUN)、血肌酐(Scr)均较治疗前改善。结论心肾综合征患者在常规抗心力衰竭治疗基础上,加用乌拉地尔、多巴胺、呋塞米联合静滴,显示改善心肾综合征患者的心肾功能。

ObjectiveTo evaluate the effect of treatment by urapidil, dopamine and furosemide on cardiorenal syndrome. Methods 25 patients with cardiorenal syndrome failed to the therapies of diuretics, vasodilating agents, and digitoxin were given urapidil, dopamine and furosemide intravenously, and the effect was assessed after 7 days treatment. Results The heart function was markedly improved after urapidil, dopamine and furosemide administration, and the total effective rate was 92%. Left heart faction index assayed by echocardiography, and BUN, Scr by biochemistry assay, were all improved as compared with before treatment （P〈0. 05）. Conclusion The cardiorenal function will be greatly ameliorated by urapidil, dopamine and furosemide in addition to conventional therapies for patient with cardiorenal syndrome.