孕期疟原虫感染对妊娠结局及母儿的影响

Gestation period malarial parasite infection affects the pregnancy result and the mother and infant

目的了解孕期疟原虫感染对妊娠结局及母儿的影响。方法选择孕期疟原虫感染248例(观察组)及正常孕妇216例(对照组)为调查对象。比较两组对象在妊娠结局、母体贫血、孕妇死亡、新生儿出生体重及新生儿窒息等方面的差异。结果观察组流产、早产、死胎发生率及孕妇死亡率高于对照组(均P<0.05);观察组引起妊娠贫血与对照组比较无统计学意义,但观察组引起中、重度贫血多于对照组,差异有统计学意义;观察组中低体重新生儿的出生率明显高于对照组,但观察组新生儿窒息的发生与对照组差异无显著性。结论孕期感染疟原虫可增加流产、早产、死胎、新生儿低出生体重的发生,同时加重妊娠贫血,增加孕妇病死率,但对新生儿窒息影响不大。

Objective To observe the impact of gestation period malarial parasite infection on the pregnancy result and the mother and infant. Methods 248 cases of gestation period malarial parasite infection （observation group） and 216 normal pregnant women （control group） were chosen to compare the variance of pregnancy result, parent anemia, pregnant woman death, the birth weigh of newborns, and neonatal asphyxia. Results The miscarriage, premature delivery, and fetal death rates were higher in observation group than control one （P〈0. 05）. There was no significant difference in the pregnant anemia between the two groups, but there were more moderate and severe anemia cases in observation group than control one. The pregnant woman mortality rate and low birth weight newborns were higher in observation group than control one （P〈0. 05）, but the incidence of neonatal asphyxia failed to show difference between the two groups. Conclusion Gestation period malarial parasite infection will increase the incidence of miscarriages, premature delivery, fetal death, low birth weight of the newborns, aggravate pregnant anemia and increase the pregnant woman mortality rate, but have little impact on neonatal asphyxia.