复谱频域OCT成像的研究

Study on Imaging of Complex Spectral Domain Optical Coherence Tomography

采用频域技术的OCT系统,深度扫描信息由背向散射光谱的傅立叶反变换获得,简化了轴向扫描过程,从而使快速OCT成像成为可能.为了实现复杂生物组织的OCT快速成像,消除谱频域OCT的"混叠"现象、重建样品的真实层析结构,本文引入了相移干涉技术,构建了一套满量程复谱频域OCT实验系统,并为系统设计了特殊的分束镜和移相器,为最终实现复杂生物组织的OCT快速成像提供了条件.

In this paper, experiment based on complex spectral Fourier-domain OCT is carried out. Conventional time-domain OCT with single-point detection technique acquires the interference signal point and point. It is a time-consuming process to create a cross-sectional image, so this kind of scanning mode may be one of the main constraint factors for high-speed imaging. When Fourier-domain technique is performed in OCT system, depth-scan information is provided by an inversion Fourier transformation of the spectrum of the back scattering light. The time-consuming mechanical OCT depth-scan can be put aside and the video rate imaging could be possible. In order to realize high-speed imaging of OCT for complex biological tissue, eliminate the alias phenomena in the image and rebuild the true tomographic structure of specimen, the phase shifting interference technology is introduced and a full range complex spectral OCT experimental system is created. A special coating beam splitter and a high precision phase shifter are used in this system. The condition for high speed imaging is provided by these aborative designs.