药物、心理及联合治疗缓解抑郁症之比较

The Comparison of Pharmacotherapy,Psychotherapy and Combined Pharmaco-psychotherapy on Full Remission of Major Depressive Disorder

针对抑郁症治疗完全缓解率低,运用临床思维方法,依靠循证医学证据,首先分析了抗抑郁药物的选择、优化、更换和联合用药的治疗效益。然后辩证分析并比较了药物与心理治疗,以及药物与心理治疗的单独与联合应用对重性抑郁急性和长期治疗的疗效,以及严重重性抑郁、严重慢性抑郁的短期和长期疗效以及费用效益,为确定治则、选择治法提供帮助。

Of particular concern is the low rate of depression treated to full remission. Firstly, the choice of initial antidepressant therapy and optimizing, switching, and combining pharmacotherapy are analyzed by the way of clinical thinking and the evidencebased medicine. Then the efficacy and cost - effectiveness of pharmacotherapy, psychotherapy and combined pharmaco - psychotherapy on acute and long - term treatment of major depressive disorder and more severe major depressive disorder, and on acute and long- term treatment of more severe chronic depression are discriminated, verified and compared, which provides help for defining treatment principle and selecting treatment methods.