血液肿瘤的基因治疗及伦理学问题

Gene Therapy of Hematologic Neoplasm and its Ethical Problems

基因治疗是一种新的有希望的抗肿瘤治疗方法。本文首先简述基因治疗发展史,然后介绍目前尝试性用于血液系统肿瘤的反义核酸疗法、抑癌基因疗法、自杀基因疗法以及过继性免疫疗法等基因治疗方法,进一步阐述基因治疗在血液系统肿瘤患者中应用存在的伦理学问题。

Gene therapy is a new and promising treatment for a variety of malignancies. This article first simply stated the development history of gene therapy, then introduced the methods of gene therapy at present for hematologic neoplasm, such as anti-sensenucleic acids therapy, anti - oncogene therapy, suicide gene therapy and adoptive immunity therapy, and further analyzed its ethical problems in the gene therapy for the patients with hematologic neoplasm,