无抽搐电休克治疗难治性抑郁症疗效观察

An observation of clinical efficacy of modified electric convulsive therapy in treatment for refractory depression

目的:探讨无抽搐电休克(MECT)治疗难治性抑郁症的临床疗效。方法:对19例难治性抑郁症患者进行MECT治疗,用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)治疗前及每治疗两次后进行评定,用TESS量表评定副反应。结果:行不同次数电休克治疗后5例痊愈,9例显著进步,总有效率为73.7%,2例经10次治疗后疗效不明显。19例行MECT治疗的患者均无明显副反应。结论:无抽搐电休克治疗难治性抑郁症安全、高效、副反应小,值得临床应用。

Objective：To study the clinical efficacy of modified electric shock the rapy in the treatment of refractory depression. Methods：Atotal of 19 in patients with refractory depression received the treatment of modified electric shock therapy. The efficacy was evaluated with HAMD and HAMA before treatment and after two times,and side effects were evaluated with TESS. Results：After different numbers of treatments,there were 5 cases recovered, 9 cases improved significantly and 2 cases were not remarkable improvement after ten times treatments. The total of significant improvement rates was 73. 7 %, but there was not remarkable side effects in the treatment of 19 cases. Conclusion ： Modified electric convulsive therapy is of safe and well effective peculiarity in the treatment of depression in addition to slight side effects, It is worth being spread in the clinic.