22种混合有机化合物在不同温度条件下对人体健康的影响

Effects of Mixture of 22 Kinds of Volatile Organic Compounds on Human Body at Different Temperature

为研究有机化合物在不同室内空气温度条件下对人体健康的影响，作者选用１０名健康自愿受试者，在人工气候室内暴露于２２种混合有机化合物（０和１０ｍｇ／ｍ３浓度）与１８、２２和２６℃温度复合因素环境中，每天６０分钟，每周６次，连续２周。实验结果表明，在１０ｍｇ／ｍ３混合有机化合物和２６℃环境条件下，空气质量明显下降，气味强度明显增强，要求加大送风量的人数明显增多，对眼睛、鼻和皮肤有明显的刺激，鼻腔面积和容积明显减少。心理学测试、眼泪膜稳定性和细胞学检查无明显变化，表明室内温度（２６℃）和混合有机化合物对人体的健康影响有明显的协同作用。因此，评价室内空气质量的好坏，不能仅仅考虑污染空气的有机化合物，还应考虑室内环境的气象条件。

Ten healthy volunteers were exposed to mixture of 22 kinds of volatile organic compounds with concentrations of zero to 10 mg/m 3 at the temperature of 18, 22 and 26 ℃, respectively in an artificial climate room for 60 minutes a day and six days week for two consecutive weeks to study their effects on human bodies. Results showed that quality of indoor air decreased significantly, odor intensity increased, number of the subjects who need more ventilation increased, and irritation to eyes, nose and skin intensified under the mixture concentration of 10 mg/m 3 and at temperature of 26 ℃. No significant changes in psychological tests, tear film stability and cytological studies were found. Room temperature at 26 ℃ has a significant synergetic effects on human health. Therefore, quality of indoor air can not be evaluated only by organic compounds polluted in air, but by meteorological conditions.