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金属转运蛋白介导的胃癌耐药的研究进展 被引量：1

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摘要 胃癌为临床最常见的恶性肿瘤之一,肿瘤多药耐药(multidrug resistance,MDR)的产生是胃癌化疗失败的主要原因。探究肿瘤多药耐药基因的特性及肿瘤治疗的新策略,是目前肿瘤防治研究的热点。金属转运蛋白介导的MDR为MDR的重要途径之一,本文就其中所包含的金属硫蛋白(metallothionein,MT)、肝豆状核变性基因蛋白ATP7B等金属转运蛋白的生物学特性及相关胃癌耐药的研究进展作一综述。
作者 赵勉之 吴晴
机构地区 上海市第一人民医院肿瘤科
出处 《肿瘤》 CAS CSCD 北大核心 2007年第8期672-675,共4页 Tumor
基金 上海市自然科学基金项目(编号:03ZR14077)
关键词 胃肿瘤 载体蛋白质类 基因 MDR
分类号 R735.2 [医药卫生—肿瘤]
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参考文献24

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共引文献22

同被引文献20

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肿瘤
2007年 第8期

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