缺血性脑血管病患者颈动脉斑块形成与血清尿酸水平关系的研究

Study of relationship between carotid arterial plaque form and uric acid level of serum in patients with ischemic cerebrovascular disease

目的探讨缺血性脑血管病(ICVD)患者颈动脉斑块形成与血清尿酸水平的关系。方法对80例ICVD(短暂性脑缺血发作36例,脑梗死44例)患者进行颈部动脉超声检查及血清尿酸含量检测。结果有2处、≥3处颈动脉斑块患者的血尿酸浓度[(342.7±86)pmol/L、(398.7±58)pmol/L]明显高于只有1处和无颈动脉斑块的患者[(328.3±92)pmol/L、(289.5±83)pmol/L](P<0.05,P<0.01)。只有1处颈动脉斑块患者的血尿酸浓度与无颈动脉斑块患者比较差异无统计学意义(P>0.05)。结论颈动脉斑块形成的程度越重的患者其血清尿酸水平越高。

Objective To approach the relationship between carotid arterial plaque form and uric acid （UA） level of serum in patients with ischemic cerebrovascular disease （ ICVD ）. Methods 80 patients with ICVD （ 36 patients with transient ischemic attack and 44 patients with cerebral infarction） were tested by cervical part artery sonography and the UA levels of serum were detected. Results The mean UA levels in the patients with two or more carotid arterial plaques [ （ 342, 7 ± 86 ） pmol/L, （ 398.7 ± 58 ） pmoL/L, respectively ] were obviously higher than those in the patients with single or no-arterial plaque [ （328.3 ± 92 ） pmol/L, （ 289.5 ± 83 ） pmol/L, respectively ] （ P 〈 0. 05, P 〈0. 01 ）. There was no difference of UA level between the patients with no-arterial plaque and with single arterial plaque （P 〉 0. 05 ）. Conclusion The patient with more severity of carotid arterial plaque form usually has higher UA level of serum.