红景天甙对体外培养腮腺癌细胞增殖的抑制作用

Study on Salidroside Inhibiting SACC-2 Cell Proliferation of Parotid Carcinoma Cell in Vitro

目的:体外研究红景天甙作用于腮腺癌腺样囊腺癌细胞(SACC-2)后,观察SACC-2细胞的增殖情况。方法:用免疫组化的方法检测红景天甙作用前后SACC-2细胞PCNA表达情况。结果:给予红景天甙组的SACC-2细胞PCNA阳性细胞数均较未加药组明显弱,即P<0.01。结论:红景天甙能抑制SACC-2细胞增殖,可能作为腮腺癌治疗的药物之一。

Objective： To study SACC -2 cell proliferation after adding salidroside in parotid carcinoma cell （adenoid cystic carcinoma, SACC- 2） in vitro. Methods： Immunohistochemistry staining is used to compare PCNA expression in SACC -2 before and after using salidroside. Results： PCNA expression is weaker in salidroside groups than in groups without salidroside （P 〈0.05 ） . Conclusion： Salidroside could inhibit SACC -2 proliferation. It may be a kind of clinical medicine to treat parotid carcinoma.