应用“妈咪爱”预防早发型母乳性黄疸的临床观察

Clinical observation of preventing early breast milk jaundice by Mamiai

目的:探讨应用肠道微生态制剂干预早发型母乳性黄疸,预防新生儿高胆红素血症的临床价值。方法:随机选择289例正常产正常新生儿作为干预组,在按需喂养的同时给予口服肠道微生态调节剂"妈咪爱",同时随机选择175例正常产正常新生儿作为对照组,给予正常开奶,按需喂养,不给予任何干预措施。1次/d监测胆红素值。结果:观察组1周内发生高胆红素血症的发生率及生后第7天血清总胆红素平均水平均明显低于对照组(χ2=4.619,P(0.05;t=-1.923,P(0.05)。结论:口服"妈咪爱"干预早发型母乳性黄疸,可有效地减少新生儿高胆红素血症的发生率及减轻新生儿生理性黄疸的程度,从而减少高胆红素血症对新生儿的早期危害。

Objective： To study the values of intestinal microeco - agent preventing early breast milk jaundice and hyperbilirubihernia. Methods： 464 cases were randomly divided into interference group （289 cases, treatings） and control group （175cases, controls） . Treatings were given by Mamiai, but nothing for controls. The bilirubin was tested once a day for both groups. Results： The rate in case whose TBIL≥220. 6μmol/L was 10. 25% in treatings, compared with 21.06% in controls, they had significent difference （X^2 =4. 619, P 〈0. 05） . The average bilirubin levels in 7th days in treatings was lower than that of controls （t = - 1. 923, P 〈0. 05） . Conclusion： Feeding earlier with Mamiai can intervene in early breast milk jaundice, reduce the rate of hyperbilirubinemia and the level of neonatal physiological jaundice, so reduce the early hazardous of hyperbilirubinemia in neonates.