冠脉腔内超声对经皮冠脉成形术后再狭窄的评价

Evaluation of Correlation between Findings of Intracoronary Ultrasound and Restenosis after Successful Coronary Angioplasty

用冠脉腔内超声对５０例径皮冠脉成形术患者的成形部位血管腔形态进行了观察，并分析其与成形术后３～６个月时再狭窄发生之间的关系。结果表明：再狭窄组的血管腔横截面积显著小于非再狭窄组（４．９３±２．５１ｖｓ６．６８±２．９６ｍｍ２，Ｐ值＜０．０５），成形术后管腔横截面积的大小与再狭窄的程度负相关（ｒ＝－０．６８，Ｐ值＜０．０５）；而管腔最大径、最小径、残存粥样斑块横截面积及面积狭窄率则与再狭窄的发生不相关。提示：冠脉内超声所测血管腔横截面积的大小可作为评价冠脉成形术疗效的一项重要指标。

Using intracoronary ultrasound (ICUS)imaging technique, the luminal morphalogic features of coronary artery at angioplasty sites were observed in 50 patients sfter successful balloon angioplasty, and their correlation with occurrence of restenosis at 3 to 6 months after angioplasty were analysed. The results showed that luminal cross-sectional area in restenosis group was significantly smaller than in non-restenosis group(4.93±2.51 vs 6.68±2.96 mm 2, P<0.05)and that an inverse correlation was found between luminal cross-sectional area and severity of restenosis(r=0.68, P< 0.05 ). This study implies that luminal cross-sectional area measured with ICUS should be taken as an important index in evaluating effects of coronary balloon angioplasty.