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基因多态性与非创伤性股骨头缺血性坏死 被引量:1

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摘要 在人群中个体间基因的核苷酸序列存在着差异性称为基因的多态性(gene polymorphism)。可以分为DNA位点多态性(site polymorphism)和长度多态性(1ength polymorphism)两类。突变是基因多态性的一种特殊形式。在疾病的关联分析和病因学研究方面,通过比较患病群体和正常群体,如果发现两组间多态性位点的特定等位基因频率有显著差异,则表明该位点与该疾病相关联。
作者 张晖 裴福兴
出处 《中华骨科杂志》 CAS CSCD 北大核心 2007年第9期715-717,共3页 Chinese Journal of Orthopaedics
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