广西地区壮汉族代谢综合征的患病率调查

The prevalence of metabolic syndrome in Han and Zhuang Chinese in Guangxi

目的分析广西地区代谢综合征(MS)及其不同组分的患病率并比较壮汉族的区别。方法采用分层随机整群抽样的方法,于2003至2005年在广西有代表性的地区开展糖尿病横断面调查。取其中有完整资料、年龄15岁以上的27 240人列入本次MS分析。MS的诊断标准分别采用2005年国际糖尿病联盟(IDF)标准和中华医学会糖尿病学分会(CDS)于2004年提出的标准。结果(1)按IDF标准,MS总的粗患病率为13.15%,其中男性为12.41%,女性为14.11%;按2000年全国普查人口计算标化患病率为7.66%,其中男性为7.26%,女性为8.81%。按照CDS标准,MS总的粗患病率为10.75%,男13.45%,女7.28%;总标化患病率5.9%,男性7.21%,女性4.31%。MS总的患病率、男性和女性的患病率均随年龄增大而升高(p<0.01)。(2)按IDF标准,壮族MS粗患病率和标化率分别为9.91%和6.69%;汉族MS粗患病率和标化率分别为13.71%和7.99%。按CDS标准,壮族MS粗患病率和标化率分别为6.92%和4.48%,汉族MS粗患病率和标化率分别为11.32%和6.14%。MS总标化患病率均为汉族高于壮族(p<0.01)。(3)在肥胖、高血压、高甘油三酯(TG)、低高密度脂蛋白胆固醇(HDL-C)和高血糖五种代谢组分异常中,按IDF标准,总的粗患病率最高为高血压32.26%,按CDS标准则为高TG 28.39%;在27 240名调查对象中,65.82%(IDF标准)和56.13%(CDS标准)调查对象至少有一种代谢组分异常。结论广西MS粗患病率按IDF标准和CDS标准分别为13.15%和10.75%,按2000年全国人口标化患病率则分别为7.66%和5.90%。汉族MS患病率高于壮族。超过半数的调查对象至少有一项代谢组分异常。

Objective To investigate the prevalence of metabolic syndrome （MS） and its components among people aged over 15 years in Guangxi Zhuang Autonomous Region and to compare the difference between Zhuang and Han populations. Methods Adopting cluster sampling, a survey of diabetes mellitus was conducted in Guangxi from 2003 to 2005. A total of 27 240 subjects aged over 15 years with complete data, including background information of each individual, blood pressure, lipid profile, plasma glucose, blood uric acid and fasting insulin were analyzed in this study. The prevalence of MS and its components were analysed in Han and Zhuang Chinese in Guangxi. The criteria of International Diabetes Federation （IDF） in 2005 and the China Diabetes Society （CDS） in 2004 were applied for diagnosis. Results （ 1 ） The crude prevalence rates of MS according to IDF definition were 13.15% in total, 12.41% in male and 14.11% in female respectively. The agestandardized prevalence rates of MS （according to the population composition in China in 2000） were 7.66% in total, 7.26% in male and 8.81% in female. The crude prevalence rates of MS according to CDS definition were 10.75% in total, 13.45% in male and 7.28% in female respectively and the age-standar-dized prevalence rates of MS were 5.9% in total, 7.21% in male and4.31% in female. The prevalence of MS in total, male and female was increasing with age （P 〈0.01 ）. （2） The crude prevalence rate and the age-standardized prevalence rate of MS according to IDF definition were 9.91% and 6.69% respectively in Zhuang Chinese, and 13.71% and 7.99% in Han Chinese. The crude prevalence rate and the age-standardized prevalence rate of MS with CDS definition were 6.92% and 4. 48% respectively in Zhuang Chinese, and 11. 32% and 6. 14% in Han Chinese. The prevalence in total in Han Chinese was higher than that in Zhuang Chinese （P 〈 0.01 ）. （3） Among 5 factors of hypertension, hyperglycemia, obesity, hypertriglyceridemia and low high density lipoprotein cholesterol, the highest crude prevalence rate was hypertension （ 32.26% ） in total according to IDF criteria and was high TG （28.39%） in total according to CDS criteria. Of all subjects, 65.82% people had one abnormal factor at least with IDF criterion and 56.13% with CDS criterion. Conclusion （ 1 ） The crude prevalence rate of MS with IDF definition and CDS definition was 13. 15% and 10. 75% respectively in Guangxi, and the age-standardized prevalence rate of MS was 7.66% and 5.90% ; （2） The prevalence of MS in Han Chinese was higher than that in Zhuang Chinese. More than 50% subjects had at least one abnormal metabolic factor.