硫氮唑酮治疗伴ST段明显下移的室上性心律失常34例分析

Therapy of SVT with obvious ST-segment depression by diltiazem

[目的]探讨硫氮唑酮对伴有ST段下移及有心绞痛的室上性心律失常的效果及安全性。[方法]5%的葡萄糖20 mL＋硫氮唑酮10 mg静脉注射20 min（0.25 mg/m in）,继以5%葡萄糖250 mL＋硫氮唑酮40 mg静脉滴注（0.08 mg/min）,当心率正常（60-90次/min）时改为口服硫氮唑酮30 mg 3次/d。[结果]经应用硫氮唑酮治疗,窦性心律转复率78.59%。减慢心室率94.12%（心室率下降30%）。本组34例病人心绞痛症状均消失。[结论]硫氮唑酮对房室洁折返性心动过速有较好的治疗作用,治疗伴有ST段下移及有心绞痛症状的室上性快速心律失常是有效且安全的。

[ Objective] The study of effect and safety of the therapy of SVT with ST - segment depression and angina pectoris by dihiazem. [ Methods] Ⅳ for 20 minutes （0.25mg/min） with dextrose 5% 20 mL ＋ diltiazem 10 mg, then IV drop （0.08 mg/min） with dextrose 5% 250 mL ＋ dihiazem 40 mg, it is changed to OP of dihiazem 30 mg for 3 times a day when the cardiac rate back to normal ones （60 - 90 times/min）. [ Results ] Through the treatment by the application of diltiazem, the cardioversion rate of the sinus rhythm is 78.59%, the decrease of VTR reaches 94.12% （ there is a 30% decrease of VTR ）. All the 34 patients of this group got a transference cure of angina pectoris eventually. [ Conclusion] Diltiazem is a kind of selectivity CCBC; it has an effective action on the therapy of AVNRT. Since it behaves like decrease the oxygen consumption of myocardium, specific extension coronary artery, and restrains the coronary artery spasm, so it＇s defined that the diltiazem is effective and safe to the therapy of the fleetness cardiac arrhythmia with ST - segment depression and symptom of angina pectoris.