糖尿病视网膜病变玻璃体手术中应用曲安奈德的并发症观察(英文)

The complications of intravitreal triamsinolone acetonide injection in vitrectomy for proliferative diabetic retinopathy

目的:讨论糖尿病视网膜病变玻璃体手术中应用曲安奈德的并发症。方法:回顾性分析2005-02/2007-01在我院进行的18例玻璃体手术中应用曲安奈德的增生性糖尿病视网膜病变患者手术后的反应。结果:手术后随访3～6(平均4.6)mo,出现高眼压2例;假性前房积脓1例;手术后玻璃体再出血3例;3例视网膜表面及黄斑区曲安奈德沉积。结论:手术后出现的假性前房积脓、视网膜表面及黄斑区曲安奈德沉积等并发症可不用特殊处理,自行吸收。术后出现的高眼压可通过降眼压药物治疗。手术后出现的玻璃体再出血可在药物不能吸收时通过再次手术治疗。

AIM： To investigate the complications of intravitreal triamsinolone acetonide （TA） injection in vitrectomy for proliferative diabetic retinopathy （PDR）. METHODS： From February 2005 to January 2007, 18 patients （18 eyes） with PDR who were injected with TA in vitrectomy were observed retrospectively after surgery. RESULTS： During a postoperative follow-up period of 3 to 6 months （mean 4.6 months）, some complications including deposit of TA granules on the macular region and surface of the retina （3 eyes）, postoperative vitreous hemorrhage （3 eyes）, elevated intraocular pressure （2 eyes） and pseudohypopyon （1 eye）were observed. CONCLUSION： The complications after surgery such as deposit of TA granules on the macular region and surface of the retina and pseudohypopyon could be cured without any special treatment. All eyes with elevated intraocular pressure after surgery were controlled by drug. Re-operation may be an effective method for patients with unabsorbable vitreous hemorrhage after vitrectomy.