正常视力人群眼压和角膜中央厚度的关系

The correlation between the central corneal thickness and intraocular pressure in the normal vision people

目的:了解正常视力人群(视力≥5.0)眼压和角膜中央厚度之间的关系。方法:分别采用角膜超声厚度计以及非接触式眼压计对视力≥5.0的志愿者54人(108眼,男22名,女32名,年龄27.82±7.78岁)进行角膜中央厚度的测量以及眼压测量。结果:正常视力人群眼压和角膜中央厚度均呈正态分布,眼压为14.63±3.25mmHg,中央角膜厚度为547.15±31.91μm。眼压和角膜中央厚度呈正相关,r=0.441,P<0.001。线形回归方程为Y=-10.05+0.045X,其中,Y为眼压,X为角膜中央厚度。其R2=0.195,拟合效率较低。结论:国人正常视力人群的眼压和角膜中央厚度均呈正态分布,两者之间呈正相关关系。正常视力(视力≥5.0)人群的角膜中央厚度可以在一定程度上反映眼压的大小,但影响较小。

AIM： To determine the central corneal thickness （CCT） and intraocular pressure （IOP） and to examine the correlation between them in the normal vision people with visual acuity≥ 5.0 METHODS： Forty-four volunteer subjects （108 eyes, 22 male and 32 female） whose visual acuity;, 5.0 were enrolled. The mean age was 27.82±7.78 years. CCT was measured by ultrasound pachymetry and IOP by non-contact tonometer. RESULTS： CCT and IOP of normal vision people were consistent with the Gaussian distribution： lOP was 14.63 ±3.25mmHg and CCT was 547.15±31.91μm. There was significant positive correlation between the CCT and IOP （r = 0.441, P〈0.001）. The linear regression equation was Y （IOP） = -10.05±0.045X（CCT）, R^2=0.195. CONCLUSION： CCT and lOP of Chinese normal vision people are consistent with Gaussian distribution and there is significant positive correlation between lOP and CCT. The CCT of normal vision people （visual acuity ≥ 5.0） could presume the quantity of lOP to a certain extent, but with small contribution.