稀有人参皂苷compoundK研究进展

Advances in the study of ginsenoside compound K

人参皂苷compound K是二醇型人参皂苷在人体肠道内的主要代谢产物和最终吸收形式。近年来,由于其各种出色的生物活性和作用,对该化合物的研究越来越受到重视。本文对人参皂苷compound K的制备、生物活性、吸收及代谢等研究进行了详细综述。

Ginsenoside compound K is the main metabolite of protopanaxadiol type ginseng saponins in intestine after oral administration and also is the major form of protopanaxadiol saponins absorbed to the body. Recently, ginsenoside compound K has received increasing attention, because in vivo or in vitro various biological actions of anticancer, hepatoprotective and anti-inflammatory etc, have shown to be mediated by this metabolite. In this paper, the studies of preparation, bioactivities, absorption, distribution and pharmacokinetics of compound K were reviewed in detail.