骨髓活检对诊断非霍奇金淋巴瘤骨髓浸润及分期意义的探讨

Observation on bone marrow biopsy in non-Hodgkin lymphoma with bone marrow involvement and staging

目的:探讨骨髓活检切片分析在非霍奇金淋巴瘤骨髓浸润(NHLBMI)诊断及临床分期方面的价值。方法:对128例非霍奇金淋巴瘤患者行骨髓活检术,分析活检切片。结果:骨髓活检切片中非霍奇金淋巴瘤骨髓浸润的阳性率为35.9%(46例)。经骨髓活检后,16例Ⅰ～Ⅲ期提升为Ⅳ期,骨髓活检前、后Ⅳ期所占比例有明显差异(P<0.01)。结论:骨髓活检切片分析对非霍奇金淋巴瘤骨髓浸润的诊断及临床分期具有重要意义。

Objective：To study the valve of bone marrow biopsy and in non-Hodgkin lymphoma with bone marrow involvement （ NHL BMI） and staging. Methods：In this article we researched 128 patients with NHL by using the method of bone marrow biopsy. We observed those and sections. Results：35.9% （46 cases） exhibited NHLBMI in marrow sections. Sixteen cases staging Ⅰ -Ⅲ were promoted to stage IV after bone marrow biopsy, After and before bone marrow biopsy, obvious difference exists between them （ P 〈 0. 01 ）. Conclusion：Bone marrow biopsy was very important examination in patient with non-Hodgkin lymphoma with bone marrow involvement（ NHL BMI） and staging.