螺旋CT灌注成像评价肝细胞癌TACE术后活性灶血供

The Evaluation of Blood Supply of Viable Tumor Lesions of Hepatocellular Carcinoma after Transcathter Arterial Chemoembolization with CT Perfusion Imaging

目的:探讨经导管动脉化疗栓塞术(TACE)治疗肝细胞癌(HCC)后活性灶血流灌注变化。方法:对17例HCC患者于TACE治疗后7～10d行CT灌注扫描,测量肿瘤组织活性灶与正常肝组织灌注参数。结果:TACE术后肝癌活性灶与正常肝组织的HBF、MTT、HAP具有显著差异(P<0.05)。HBV、PS、HAF、PVP无显著差异,P>0.05。结论:CT灌注成像可用于评价肝细胞癌TACE术后肿瘤活性灶血供状态。

Objective To investigate the blood perfusion change of hepatocellular carcinoma （HCC） after transcatheter arterial chemoembolization（TACE）. Methods CT perfuion imaging was performed 7 ~ 10 d after TACE for 17 HCC patients . The perfusion images and parameters of viable tumor lesions and normal lesions of HCC were detected with liver tumor mode. Results The differences of HBF, MTT, HAP between two groups were statistically significant, the differences of HBV,PS, HAF,PVP were not statistically significant. Conclusion CTPI could be a new method for evaluation the blood supply of viable tumor lesions of HCC after TACE. Key words： CT perfusion; Hepatocellular carcinoma （ HCC） ; Transcatheter arterial chemoembolization （ TAC E）