宫颈癌患者宫颈粘液CEA测定的临床意义

Clinical Significance of Cervical Mucus CEA Assay in Patients with Carcinoma of the Cervix

应用放射免疫技术对50例宫颈癌患者及24例非恶性肿瘤患者的宫颈粘液及外周血CEA的含量进行了测定，结果：宫颈癌患者宫颈粘液CEA测定值及阳性率明显高于对照组（P＜0．05，P＜0．01）。良、恶性病变的宫颈粘液CEA均明显高于外周血中CEA含量（P＜0.01，P＜0．02）。而宫颈癌患者血CEA测定值及阳性率与对照组比较均无差异（P＞0．05）。宫颈癌患者治疗前、后宫颈粘液CEA测定值差异有显著性（P＜0.01）。作者认为：宫颈粘液CEA的测定对宫颈癌的诊断及疗效评价较血CEA的测定更有意义。

The CEA coto of cervical mucus patients and periphend serum was detendned in 50 cerricalareinoma patients and 24 nonmalignant tumor patients by a radioimmunoassay technique, The CEA levelsand positive rate of cervical mucus in cewical carcinoma group were significantly higher than that incontrol group (P <0.05 ana P < 0.01 respectively) .The levels of cervical mucus CEA in benigh andmalignant Patients were significantly higher than those of peripheral serum CEA(P < 0.01 and P <0.02,respectively). There was no significant no in serum CEA leve and positive rate betweencervical cance group and control group(P > 0.05). There was a significant dence about cervicalmucus CEA in cervical carcinoma Patients before and after treatment (P <0. 01 ). The writers of thisarticle think tha the CEA level of cervical mucus is a more useful index than that of the serum indiagnozing and evalusting the curative effect of cervical cancer.