417例食管上皮细胞重度增生随访性研究

A Follow-up Study of 417 Cases of Severe Esophageal Epithelial Cell Hyperplasia

本文对食管上皮细胞重度增生４１７例未经特殊治疗而进行随访性研究结果说明：重度增生的自然转归结果为１６２例转归为食管癌，占３８．８％，２８例死于其它癌。占６．７％，１６９例死于其它病，占４０．６％，５８例为现症患者，占１３．９％。对１５７例因食管癌死亡者进行癌变时间研究说明以１￣５年为多，占５６．１％，其平均癌变时间为３年６月。

Four hundred and seveteen cases of sever esophageal epithelial cell hyperplasia without speifictreatment were studied by means of follow-up. The results indicaed that the final results of the naturalcourse of the severe esophageal epithelial cell hyperplasia were esophageal cancer (38. 8%, 162/417),death of other diseases(40. 6%, 169/417), death of other cancers (6. 7%,28/417)and ekisting patientswith edageal epthelial cell hyperlasia(13. 9%, 58/417). 58 existing current patients with esophagealepithelial cell hyperplasia were investigated by cytopathology, the results were as follws: 33 cases werewith normal esophageal epithelia(56. 9% ), 16 with slight esophageal epithelial hyerplasia(27. 6% ). Iwith esophageal carcinoma (1 .7% ) and 8 missed the follow-up (13.8% ) .Such a large scaled follow-upstrdy of the sever esophageal epithelial cell hyperplasis has not been seen at home and abroad.