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胡黄连提取物降酶作用的研究 被引量:2

The Function of Reducing GPT by the Rhizoma Picrorhiza Kurrooa Extract
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摘要 采用有机溶剂提取和柱层析分离等方法分离提取到胡黄连中的活性成分,经初步观察,胡黄连提取物对四氯化碳和硫代乙酰胺所致小白鼠急性肝损伤时谷丙转氨酶活性升高均有显著抑制作用。 Effective constituents of Picrorhiza Kurrooa were obtained by using organic solvents extraction and subsequent column chromatography. For pharmacological studies, the aqueous solution of the extract was used. The results showed that it signicantly restrained the elevation of GPT in serum caused by CCl 4 and thioacetamide induced hepatic damage in mice.
出处 《时珍国药研究》 CSCD 1997年第1期18-19,共2页
关键词 胡黄连 急性 肝损伤 谷丙转氨酶 药理 Picrorhiza kurrooa Acute hepatic damage GPT
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参考文献1

  • 1李仪奎.中药药理实验方法学[M]上海科学技术出版社,1991.

同被引文献32

  • 1贺震旦,杨崇仁,王答祺,冯宝树.西藏胡黄连的化学成分(英文)[J].云南植物研究,1993,15(1):83-88. 被引量:35
  • 2张希恩,王利华.大黄保肝利胆作用的药理与临床[J].中医药研究,1995,11(4):56-59. 被引量:24
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  • 6R. Anandan,T. Devaki. Hepatopmtective effect of Picronrrhiza kurroa on tissue dofence system in D- galactosamine- induced hepatitis in rats[J]. Fitoterapia, 1999,70( 1 ) :54.
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