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几个真核生物启动子计算机预测数据库资源概述 被引量:8

The Introduction of Several Eukaryotic Promoters Databases
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摘要 启动子是基因表达调控的重要元件,深入研究启动子的结构和功能,是理解基因转录调控机制和表达模式的关键。随着生物技术和计算机技术的高速发展,应用生物信息学技术对启动子进行预测和分析的方法得到了很大发展。简单介绍了目前常用的真核生物启动子预测相关数据库和软件资源。 Eukaryotic promoters are important elements in regulation of the expression.To study the structure and function of a promoter deeply is the key to know how the gene regulates its transcription and starts its expression.With the fast development of biological and computer technology,significant achievements have been made in computational prediction on Eukaryotic promoters.This paper mainly introduced the progress made in the databases of predicting Eukaryotic promoters as well as the related software resources.
出处 《湖南农业科学》 2007年第4期70-71,74,共3页 Hunan Agricultural Sciences
关键词 真核生物 启动子 数据库 预测 wikipedia promoter database prediction
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参考文献5

  • 1Christoph D,Viviane P.The eukaryotic promoter database EPD:the impact of in silico primer extension[J].Nucleic Acids Research,2004,32:82-85.
  • 2Kenichi H,Yoshihiro U.Plant cis-acting regulatory DNA elements (PLACE) database[J].Nucleic Acids Research,1999,27(1):297-300.
  • 3Kolchanov N A,lgnatieva E V.Transcription regulatory regions database (TRRD):its status in 2002[J].Nucleic Acids Research,2002,30(1):312-317.
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  • 5Tompa M,LIN,Bailey T L,et al.Assessing computational tools for the discovery of transcription factor binding sites[J].Nature Biotech,2006,23:137-144.

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