广东省人群中人嗜T细胞病毒Ⅰ型感染的血清流行病学调查及其与人类疾病的关系

A seroepidemiological survey: Antibody to HTLV-1 in sera from various populations in Guangdong Province

收集广东省各类人群血清标本２２２４份，用间接免疫荧光法检测人类嗜Ｔ细胞病毒Ⅰ型（ＨＴＬＶ－１）抗体，结果：ＨＴＬＶ－１抗体阳性３５份，总阳性率为１．５７％；其中健康人群血清１８１０份，抗体阳性２３份，阳性率为１２７％；献血员血清２４８份，抗体阳性１份，阳性率０４０％；白血病患者血清１０９份，阳性８份，阳性率７３４％，与健康人群比较，有非常显著性差异（Ｐ＜０００５）；神经系统疾病患者血清５７份，阳性３份，阳性率５２６％。

A seroepidemiological survey of HTLV-1 infection in Guangdong Province was reported. 2224 serum samples from various populations were collected and antibodies to HTLV-1 in sera were detected with indirect immunofluorescent assay. Total seropositive rate was 1.57% (35/2224). The antibody positive rates of HTLV-1 in sera from healthy individuals (n=1810)、blood donors (n=248)、patients with T cell leukemia (n=109) and patients with neurological diseases (n=57) were 1.27%, 0.40%, 7.30% and 5.26% respectively. There was a significant difference between the patients with T cell leukemia and the healthy individuals (P<0.005).