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2型糖尿病患者血清hsCRP和IL-18与大血管病变的相关性 被引量:3

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摘要 目的:探讨高敏C反应蛋白(high-sensitivity C-reactive protein,hsCRP)、白介素18(In—terleukin-18)与2型糖尿病并发大血管病变的相关性。方法:收集72例2型糖尿病(DM)患者和36例健康对照,分别测定各组血清hsCRP和IL-18的水平,并进行相关性分析。结果:2型糖尿病组hsCRP和IL-18水平显著高于健康对照组,具有显著性差异(P〈0.01),并发大血管病变患者hsCRP和IL-18较无大血管病变者有显著性意义(P〈0.05),相关分析:血清IL-18与hsCRP(r=0.240,P〈0.05),hsCRP与空腹血糖(FBG)(r=0.300,P%0.05)正相关。结论:hsCRP与IL-18在2型糖尿病并发大血管病患者中升高,可能在2型糖尿病的发病及进展过程中起到重要的作用。
作者 赵硕生
出处 《国际检验医学杂志》 CAS 2007年第8期754-755,共2页 International Journal of Laboratory Medicine
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参考文献7

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二级参考文献19

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