丹参粉针剂联合营养支持治疗心衰并心源性营养不良的临床研究

Clinical study of congestive heart failure accompanied with malnutrition With danshenfenzhen and nutritional support

目的探讨在常规治疗慢性心力衰竭的基础上,应用丹参粉针剂联合营养支持治疗对慢性心衰并心源性营养不良的治疗意义。方法随机选择42例慢性心衰和并营养不良患者,将其分为自由饮食组和丹参粉针剂加营养支持组。自由饮食组随意进食,丹参加营养支持组按计算的总能量消耗进行营养支持,并给予丹参粉针剂静点,观察血浆白蛋白、淋巴细胞总数、体质量。结果 42例患者人院时均有不同程度的营养不良,治疗第14天后,自由饮食组血浆白蛋白、体质量和淋巴细胞计数明显下降;丹参加营养支持组血浆白蛋白、体质量和淋巴细胞计数明显上升。结论心衰治疗同时静点丹参粉针剂加营养支持,可提高血浆白蛋白的浓度,增加体质量,改善免疫状态,提高心衰的治疗效果。

Objective To observe the clinical therapeutic effect of danshenfenzhen and nutritional support in treating congestive heart failure accompanied with malnutrition on the basis of common treatment. Methods 42 cases of congestive heart failure accompanied with malnutrition were randomly divided into 2 groups ： test group 21 cases （danshenfenzhen and nutritional support） and control group 21 cases（free diet）. In the test group intravenous drip danshenfenzhen and vein nutrition were given if the internal nutrition can not provide enough energy on the basis of count of energy consumption, the serum albumin, total blood lymph cells and body weight were measured. Results After 14 days＇ treatment in the test group, the serum albumin, body weight and the total lymph cell increased significantly while in the control group, the serum albumin, body weight and the total lymph cells decreased significantly. Conclusion Intravenous drip danshenfenzhen and nutritional support can improve nutritional status＇ and cardiac function of patients with congestive heart failure accompanied with malnutrition.