子宫动脉栓塞术治疗子宫肌瘤的疗效

The curative effect in patients with uterine ieiomyoma by uterine artery embolization methods

目的探讨子宫动脉栓塞术(UAE)治疗子宫肌瘤的疗效及安全性。方法对40例子宫肌瘤患者行 UAE 治疗,随访3～6个月观察治疗前后肌瘤体积变化与原有症状的改善情况并监测血中卵巢激素的水平。结果 40例患者行 UAE 的改善率为85.0%(34例)。栓塞后,小肌瘤组平均肌瘤缩小率要高于大肌瘤组,但两者间无明显统计学差异,且这种差异又有随着时间缩小的趋势。术后无患者出现闭经,栓塞前后激素水平无显著变化。结论行 UAE 治疗子宫肌瘤,近期疗效明显,且对卵巢内分泌功能无影响。

Objective To evaluate the effects and safety of uterine artery embolization for uterine leiomyoma. Methods Total of 40 patients with uzerine leiomyoma was treated by UAE. They were followed up for 3 to 6 months to observe the changes of leiomyoma size and the menses resumption. Analysis of variance was used to detect differences in ovarian hormones levels before and after UAE. Results Bilateral embolization of the uterine arteries was performed in 40 patients;the clinical symptomatic improvement was observed in 34 cases（85.0 % ）. The larger dominant leiomyoma volume was associated with a smaller percentage reduction in volume at 3 months and 6 months, this difference, which was not statistically significant, was decreased with time. No amenorrhea occurred during the period of observation. No significant difference in ovarian hormones level between pre and post embolization was seen. Conclusion UAE is an effective and safe therapeutic procedure, which has no adverse effect on the ovarian function.