川芎中含阿魏酸效应组分的提取、纯化工艺研究

Studies on extraction and purification of active parts of ferulic acid from Ligusticun chuanxiong

目的:对川芎中含阿魏酸效应组分的提取、纯化工艺进行优化研究。方法:以阿魏酸为主要指标,采用单因素及正交试验设计考察提取工艺参数的最佳组合;采用单因素试验考察大孔树脂吸附法的纯化工艺参数。结果:纯化后含阿魏酸效应组分的出膏率为1.67%,其中含阿魏酸5.82%。结论:本实验研究为川芎药材及其制剂的开发提供有益的实验依据。

Objective： To study on the process of extraction and purification of active parts from Ligusticun chuanxiong. Method： The processes of extraction and purification of active parts of ferulic acid were optimized by direct comparison and orthogonal design. Result： Extract rate of active parts of ferulic acid was 1.67% and the content of ferulic acid was 5.82%. Conclusion： Active parts of ferulic acid from L. chuanxiong were extracted and purified effectively.