紫牛肝菌子实体化学成分研究

Chemical study on fruiting bodies of Boletus vioaceo-fuscus

目的:研究紫牛肝菌Boletus vioaceo-fuscus子实体的化学成分。方法:紫牛肝菌丙酮提取物经柱色谱分离并根据波谱数据鉴定化合物的结构。结果:分离鉴定了6个化合物,分别是3β-羟基-麦角甾-5,7,22-三烯(1),琥珀酸酐(2),(22E,24R)-5α,6α-过氧麦角甾-8,22-二烯-3β,7α-二醇(3),(22E,24R)-5α,6α-过氧麦角甾-8(14),22-二烯-3β,7α-二醇(4),脑苷酯B(5)和腺嘌呤核苷(6)。结论:以上所有化合物均为首次从该真菌中分离得到。

Objective： To investigate the chemical constituents of Boletus vioaceo-fuscus. Method： The compounds were isolated with column chromatography. The structures were determined by spectroscopic techniques. Result： Six compounds were isolated from the fruiting bodies of Boletus vioaceo-fuscus. They were identified as ergosta-5, 7, 22-triene-3β-ol （ 1 ）, dihydrofuran-2, 5-dione （2）, （22E, 24R） -5α, 6α-epoxyergosta-8, 22-diene-3β, 7α-diol （3）, （22E, 24R） -5α, 6α-epoxyergosta-8 （ 14 ）, 22-diene-3β, 7α- diol （4）, cerebroside B （5） and adenosine （6）, respectively. Conclusion： All the Compounds were obtained from the fruiting bodies of Boletus vioaceo-fuscus for the first time.