中西医结合治疗重症肌无力危象42例疗效观察

Combination of Traditional Chinese Medicine and Western Medicine for Myasthenia Gravis Crisis:An Observation of 42 Cases

目的:观察中西医结合治疗重症肌无力危象(MGC)的临床疗效。方法:将84例患者随机分为2组各42例,治疗组采用中西医结合治疗,对照组采用纯西药治疗,2组均治疗4周,治疗结束时评定近期疗效,3月后评定远期疗效。结果:近期疗效总有效率治疗组为95.24%,对照组为85.71%;远期疗效总有效率治疗组为88.10%,对照组为66.67%。2组近期疗效比较,差异有显著性意义(P<0.05);2组远期疗效比较,差异有非常显著性意义(P<0.01)。提示治疗组近、远期疗效明显优于对照组。结论:中西医结合治疗重症肌无力危象,临床疗效显著且作用持久。

Objective:To observe the therapeutic effect of traditional Chinese medicine(TCM)combined with western medicine(WM)for the treatment of myasthe- nia gravis crisis(MGC).Methods:Eight-four MGC patients were equally random- ized into two groups:the treatment group received TCM-WM therapy and the control group was treated with WM only.After 4-week treatment,the short-term effect was observed,and the long-term effect was evaluated 3 months after treatment.Results: Short-term effective rate was 95.24% in the treatment group and 85.71% in the control group;long-term effective rate was 88.10% in the treatment group and 66.67% in the control group.The difference of short-term and long-term effect was significant between the two groups(P<0.05).Conclusion:The combination of TCM-WM is effective for MGC and has long-term effect.