3Potter WZ,Ketter TA.Pharmacological issues in the treatment of bipolar disorder:focus on mood-stabilizing compounds[J].Can J Psychiatry,1993,38(Suppl 2):S51-S56
4Chen LC,Chou MH,Lin MF,et al.Lack of pharmacokinetic interaction between valproic acid and a traditional Chinese medicine,paeoniae radix,in healthy volunteers[J].J Clin Pharm Ther,2000,25(6):453-459
5Bachmann KA,Genotyping and phenotyping the cytochrome p-450 enzymes[J].Am J Ther,2002,9(4):309-316
6Wen X,Wang JS,Kivisto KT,et al.In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms:preferential inhibition of cytochrome P450 2C9 (CYP2C9)[J].J Clin Pharmacol,2001,52(5):547-553
7Jessica F,Manoranjenni C.Psychotropic drug interactions with valproate[J].Clin Neuropharmacol,2005,28(2):96-101
8Ingelman-Sundberg M.Pharmacogenetics of cytochrome P450 and its applications in drug therapy:the past,present and future[J].Trends Pharmacol Sci,2004,25(4):194-199
9Fukushima-Uesaka H,Saito Y,Watanabe H,et al.Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population[J].Hum Mutat,2004,23(1):1-8
10Anderson GD.Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs[J].Neurology,2004,63(Suppl 4):S3-S8
2De Morais S, Wilkinmn GR, Blaisdell J. et al. The major genetic defect responsible for the polymorphism of S - mephenytoin metabolism in humans [J]. J Biol Chem, 1994, 269(22): 15419-15422.
3Kunihiko IT, Kazuyuki IN, Hiroshi NK, et al. Polymerase Chain Reaction-Single-Strand conformation po|ymorphism based determination of two major genetic defects responsible for a phenotypic polymorphism of cytochrome P450 (CYP) 2C19 in the japanese population[J ]. Analytical Biochemistry, 2000, 284( 1 ) :160.
4Kristensen VN, Kelefiotis D, Kristensen T, et al. High-throughput methods for detection of genetic variation[J]. Biotechniques 2001,30(2) :318,324,326.
9Lee SG, Kim JH, Joo JY, et al. Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics[J]. Korean JLab Med, 2007,27 (5):338.
10Haroutiunian S, Ratz Y, Rabinovich B, et al. Valproic acid plasma concentration decreases in a dose-independent manner following administration of meropenem: a retrospective study[J]. J Clin Pharmacol, 2009,49( 11 ) : 1 363.