认知疗法合并黛力新治疗脑卒中后焦虑的疗效

The effect of cognitive therapy with Deanxit in post-stroke anxiety disorder treatment

目的评价认知疗法合并黛力新(氟哌噻吨/美利曲辛)治疗脑卒中后焦虑的疗效。方法将80例脑卒中后焦虑患者随机分为治疗组(n=40)和对照组(n=40),分别给予认知疗法合并黛力新、单用黛力新治疗8周。用汉密顿焦虑量表、副反应量表分别评定疗效和副反应。结果治疗4、8周时,治疗组汉密顿焦虑量表评分(16.08±7.45,8.80±4.73)明显低于对照组(19.80±8.26,11.35±5.03),P<0.05;临床总疗效无论治疗4、8周,治疗组均优于对照组,P<0.01。结论认知疗法合并黛力新治疗脑卒中后焦虑的疗效较好。

Objective To explore the effect of cognitive therapy with Deanxit （Flupentixol/ Melitracen） in post--stroke anxiety disorder treatment. Methods 80 post-stroke anxiety disorder patients were divided into treating group（40） and control group（40） randomly, treated with cognitive therapy and Deanxit or Deanxit only for 8 weeks respectively, and evaluated the anxiety and side effects with Hamilton Anxiety Scale （HAMA） and Rating Scale for Side Effects （SERS）. Results After treated for 4 and 8 weeks, the score of Hamilton Anxiety Scale of treated group （16.08±7.45, 8.80±4.73） were obviously lower than those of control group （19.80±8.26, 11.35±5.03 P〈0.05 ）, and the whole therapeutic effectiveness in treated group after 4 and 8 weeks were better than those of control group （P〈 0.01） . Conclusions Cognitive Therapy with Deanxit in post--stroke Anxiety Disorder Treatment has an preferable effects.