摘要
合成了乙二醛缩双(邻氨基苯酚)合锰(II)配合物,讨论了其在DMF中的载氧行为、氧合动力学;设计正交试验考察了以分子氧为氧源,该配合物催化氧化醋酸去氢表雄酮生成7-酮基醋酸去氢表雄酮的性能,最高收率达78.4%.
Bis（2-hydroxyphenyliminomethyl） manganese complex was prepared and its oxygenation performance in DMF solution was studied. In the presence of the manganese complex, dehydroepiandrosterone acetate was effectively oxidized to 7-keto-dehydroepiandrosterone acetate by molecular oxygen. Orthogonal experiments were designed to investigate the influences of four factors on yield of the target product. The highest yield obtained reached 78.4%.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2007年第9期1106-1109,共4页
Chinese Journal of Organic Chemistry
基金
中南大学博士后科学基金(No76132020)资助项目
关键词
席夫碱锰配合物
合成
氧合
仿生氧化
醋酸去氢表雄酮
Schiff base manganese complex
synthesis
oxygenation
aerobic oxidation
dehydroepiandrosterone acetate
