大鼠巨细胞网状核与脑干眼球外肌运动神经核的纤维联系

Fibrous connections between the gigantocellular reticular nucleus and the motor nucleus of cranial nerves that control the oculomotor muscles in the rat

目的:观察大鼠脑干网状结构抑制区巨细胞网状核与脑干眼球外肌运动神经核的纤维联系。方法:将2种神经元示踪剂麦芽凝集素-辣根过氧化物酶(WGA-HRP)、1,1'-双十八烷-3,3,3',3'-四甲基吲哚羰花青-高氯酸盐(DiI)分别注入大鼠左侧巨细胞网状核后,镜下观察示踪剂在脑干眼球外肌运动神经核的分布。结果:WGA-HRP逆行标记神经元胞体及顺行标记神经纤维终末出现于双侧动眼神经核、滑车神经核,标记胞体同侧多于对侧;动眼神经核小细胞部也发现逆行标记细胞;展神经核未见标记。2种示踪剂显示结果基本一致。结论:大鼠巨细胞网状核与脑干眼球外肌运动神经核有直接纤维联系。

Aim ： To observe the fibrous connections between the gigantocellular reticular nucleus（NRG） and the motor nucleus of cranial nerves that control the ocuh, motor muscles in the rat. Methods：The two bidirectional tracers WGAHRP and DiI were respectively used to map the path. The two tracers were respectively transfused into the left side of NRG, and the distributions of 2 tracers were observed under the light microscope. Results： The retrogradely labeled neurons and antrogradely labeled fibers were found in double sides of both nucleus of oculomotor nerve and nucleus of trochlear nerve,in addition,the number of the labeled cells at the same side was more than that at the other side. There were the labeled cell bodies in the parvicellular part of nucleus of oculomotor nerve. The nervous signal was not discovered in the abducens nucleus. The marks of the two tracers were basicly consistent. Conclusion ： The NRG and the motor nucleus of cranial nerves that control the oculomotor muscles in thc rat have straight fibrous connection.