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120株产β-内酰胺酶金色葡萄球菌的耐药分析 被引量:2

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摘要 目的对细菌培养分离出产β-内酰胺酶金色葡萄球菌菌株进行药物敏感试验分析,为临床使用抗生素提供依据。方法严格按照《全国临床检验操作规程》的要求接种,对分离出的120株金色葡萄球菌,用头孢菌素显色法测定其β-内酰胺酶。结果120株金色葡萄球菌中产β-内酰胺酶92株,产酶率76.7%,产酶株除对万古霉素、替考拉宁、利福平及复方新诺明敏感外,对其它的抗生素均呈不同程度耐药,其中青霉素G、氨苄青霉素耐药率均为98.2%,红霉素为85.4%。结论产β-内酰胺酶胺酶株对青霉素大环内酯类抗生素呈现高度耐药,因此临床治疗时不宜使用此类抗生素,提示临床医生应在药敏试验的指导下合理选择抗生素。
出处 《海南医学》 CAS 2007年第10期134-135,共2页 Hainan Medical Journal
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