福辛普利最佳服用时间的相关性研究

Study on the relativity of optimal time to take fosinopril

目的研究2种服药时间对血压的影响。方法随机将42例服用长效降压药的高血压患者分为2组。对照组采用传统方法,即进餐后半小时服药。观察组采用清晨起床后空腹服药。2组患者均在6∶00、8∶00、14∶00、18∶00、22∶00、2∶00进行血压测量。结果2组总的降压疗效无显著性差异（P〉0.05）,但在控制清晨高血压的疗效上,观察组优越于对照组（P〈0.05）。结论选择最佳服药时间,对降压非常有意义。

Objective To study the eftect on blood pressure of two different time of taking medicine.Methods 42 patients with hypertension who took hypotensive drug of prolonged action were divided into two groups. Observation group took medicine on empty stomach after getting up in the morning. Control group took medicine about 30 minute after breakfast. Blood pressure of two groups was measured at 6∶00,8∶00,14∶00,18∶00,22∶00,2∶00.Results There was no significant difference in the depressurization effect, however, there was a significant difference in the control of morning hypertension, Observation group are obviously better than the control group.Conclusions It plays important role on blood pressure to select the optimal time to take medicine.