南京市区消化科医护人员中幽门螺杆菌感染的流行病学调查

Prevalence of Helicobacter Pylori(Hp) Infection in the Department of Gastroenterology Staff Members in Nanjing

通过检测末梢血抗幽门螺杆菌（Hp）IgG的方法，调查了南京市区102名消化科医护人员和130名非消化科医护人员的Hp感染状况。发现前者光密度值（0.71±0．29）非常显著地高于后者（0．49±0．28）（P＜0．005）；在消化科或内镜室工作＜5年、5～10年、＞10年的3组人群之间不存在显著性差异；消化科医生与护士比较（P＞0.05），内镜人员与普通消化科人员比较（P＞0.05），亦未显示显著性差异。初步认为：（1）消化科人员在医患接触中Hp感染的危险性高于医院内其他人群；（2）从事消化科临床工作5年之内获得Hp感染的危险度即已达到饱和值水平；（3）使用手套可能会降低医患接触过程中Hp感染的传播。

The present study was carried out by measuring anti-Hp IgG in peripheral blood from fingers.Two hundred and thirty - two subjects working in six hospitals in Nanjing were investigaed,including 102 gastroenterologists and gastroenterology nurses (G group), 130 nongastroenterology practioners (NG group). Results showed: (1) Optical density level of G group (0.71±0. 29) was significantly different from that of NG group (0. 49±0.28 ) (P < 0.005); (2) Among G group:doctors compared with nurses (P >0.05); endoscopists compared with general practioners(P>0.25); among three subgroups, divided by their working years in gastroenterology field or endoscopy room as less than 5 years, 5 - 10 years or more than 10 years, with no significant differences. Conclusions:(1)Department of Gastroenterology staff members have a higher risk of Hp infection than other groups in hospitals. (2) The risk of gastroenterologists or gastroenteroogy nurses infected by Hp would reach maximum after 5 years of working. (3) Using gloves in clinic practice might reduce the incidence of Hp infection.